Metal‐Free Synthesis of Thiosulfonates via Insertion of Sulfur Dioxide

A simple and catalyst‐free strategy was developed for the synthesis of unsymmetrical thiosulfonates using readily available DABCO⋅(SO 2 ) 2 as a solid and bench‐stable sulfur dioxide surrogate. The corresponding thiosulfonates were obtained through a radical pathway with good functional group tolerance. This strategy offers a promising synthesis method for the construction of diverse and useful thiosulfonates in the field of synthetic and pharmaceutical chemistry and extends the number of still limited sulfur dioxide fixation strategies. magnified image