Influence of age and gender on the pulse waveform in optic nerve head circulation in healthy men and women

Figures

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  Figure 1. Analyzing the pulse waveform in the ONH circulation using LSFG. The gray-scale map of the total measurement area. The circle is the area of the ONH (A). (B) The software separates out the retinal vessels by using an automated definitive threshold throughout the ONH, within the ONH vessel (shown in white), and within the ONH tissue (black). The pulse waves show changes in the MBR, which is tuned to the cardiac cycle for 4 sec. The total number of frames is 118. Finally, the software calculates the normalization of one pulse. The pulse waveform analysis in the ONH-Vessel, Tissue. and whole of ONH (All) are calculated on this screen (C).

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  Figure 2. Schematic explanation of the BOS, BOT, ATI, and rising rate obtained from the pulse waveform analysis in the ONH.

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  Figure 3. Chronological changes in MABP, pulse pressure, heart rate, and BOT-Tissue in both genders. ●: men. ○: women. Error bars: Standard error. *p < 0.05, \documentclass[12pt]{minimal} \usepackage{amsmath} \usepackage{wasysym} \usepackage{amsfonts} \usepackage{amssymb} \usepackage{amsbsy} \usepackage{mathrsfs} \usepackage{upgreek} \setlength{\oddsidemargin}{-69pt} \begin{document}$${}_{\ast }{}^{\ast }{\rm{P}} < 0.001$$\end{document}P⁎⁎<0.001, ⁂p < 0.0001 between the men and women by unpaired t-test. The MABP was higher in the men than in the women until the age of 61 years, and the pulse pressure in the women was higher than in the men at age >51 years. There was no difference in BOT-Tissue until the age of 40 years, but among the subjects aged ≥41 years the BOT-Tissue values in the women were significantly lower than those in men.