Why the study?
What are the conventional and emerging cardiovascular risk factors that explain the high risk of coronary artery disease among South Asians?
What are the conventional and emerging cardiovascular risk factors that explain the high risk of coronary artery disease among South Asians?
South Asians have a disproportionately high risk of CAD that may not be fully explained by conventional risk factors, necessitating the evaluation of emerging risk factors to optimize management.
May support ethnicity-specific CAD risk assessment in South Asians; leaves open validation of emerging factors in prospective studies.
South Asians (SAs), in their countries or after migration, are at high risk of coronary artery disease (CAD) and mortality compared to other ethnic groups. It has been shown that >90% of CAD global risk could be attributed to 9 modifiable risk factors (RFs) worldwide. However, these conventional RFs may not fully explain this high risk of CAD among SAs. Therefore, attention has been directed toward nonconventional RFs. In this narrative review, we evaluate the conventional and emerging cardiovascular RFs characterizing SAs. These factors may explain the high morbidity and mortality among SAs. Further prospective studies are urgently needed to set algorithms for the optimal management of these RFs in high-risk populations like SAs.
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Ahmed et al. (2014) studied this question.
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