May 1, 1961Circulation Research

Electrocardiographic Effects of Changing the Nature of the Contact Between the Exposed Heart and the Body

View Full Paper

Ask AI

Bookmark

Population

Dog models in open-chest experimental situations

Comparison

Addition of ventricular surface to the… vs Maximally insulated heart

Design

Preclinical

Authors

JSJOHN J. SAŸENHospital of the University of Pennsylvania AKAaron Honori KatcherUniversity of Maryland, Baltimore GPGeorge J. PeirceUniversity of Pennsylvania

Discussion

Member takes

Implication

Alerts to contact-area effects on R-wave in open-chest animal models; leaves open clinical translation and standardization needs.

Structured PICO

Population

Dog models in open-chest experimental situations

Intervention

Addition of ventricular surface to the heart-body contact area (removal of insulation) and local physiological alterations (including regional ischemia)

Comparator

Maximally insulated heart (connected to the body only by its vascular pedicle)

Outcome

Electrocardiographic representation (R-wave amplitude and local lead changes)surrogate

The degree of insulation between the exposed heart and the body in experimental dog models significantly affects electrocardiographic recordings, particularly R-wave amplitude.

Cite This Study

SAŸEN et al. (1961) studied this question.

synapsesocial.com/papers/6a760e7cfa1990f79e613c11 https://doi.org/10.1161/01.res.9.3.497

View Full Paper

Ask AI

Bookmark

Electrocardiographic Effects of Changing the Nature of the Contact Between the Exposed Heart and the Body

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Electrocardiographic Effects of Changing the Nature of the Contact Between the Exposed Heart and the Body

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Also Consider

Also Consider