Why the study?
Does levarterenol affect epicardial electrocardiograms and ventricular contractility in open-chest dogs?
Population
open-chest dogs with nonischemic, regionally ischemic, and hypoxic myocardium
Design
Preclinical
Authors
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May confound ECG assessment of ischemia during catecholamine use; leaves open translation from canine models to humans.
Does levarterenol affect epicardial electrocardiograms and ventricular contractility in open-chest dogs?
In an open-chest dog model, levarterenol increased ventricular contractility and produced RS-T segment depression regardless of baseline myocardial ischemia or hypoxia.
SAŸEN et al. (1960) studied this question.
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