Heparin-induced thromboembolism presents with distinctive angiographic features characterized by broad-based, lobulated mural filling defects causing significant luminal narrowing proximal to occlusions.
May aid recognition of heparin-induced thromboembolism; Level 5 evidence leaves open prospective validation.
Angiographic evaluation of heparin-induced thromboembolism in 3 patients who suffered disastrous consequences revealed a distinctive radiographic appearance consisting of mural filling defects quite unlike atheromatous plaques. These lesions were broad-based, isolated, gently lobulated excrescences which produced 30-95% narrowing of the arterial lumen. In eache case, the lesions were located proximal to sites of arterial occlusion.
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Lindsey et al. (1979) studied this question.
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