Why the study?
Does infrarenal aortic abdominal aneurysm repair induce a systemic inflammatory response and impair pulmonary function compared to major abdominal surgery?
Does infrarenal aortic abdominal aneurysm repair induce a systemic inflammatory response and impair pulmonary function compared to major abdominal surgery?
Infrarenal aortic surgery induces early local gene activation of inflammatory and renin-angiotensin system components in ischemic muscle, leading to systemic IL-6 release and subsequent pulmonary dysfunction.
Aortic surgery was associated with higher IL-6 and worse oxygenation ratios than abdominal surgery; hypothesis-generating for inflammation-mediated lung injury in vascular patients.
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Adembri et al. (2004) studied this question.
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