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February 15, 1996The Journal of Cell BiologyOpen Access

Potential sites of PI-3 kinase function in the endocytic pathway revealed by the PI-3 kinase inhibitor, wortmannin.

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Authors

HSHoward S. ShpetnerFoundation for Biomedical ResearchMJMarguerite JolySanofi (France)DHDavid A. HartleyGuyana School of Agriculture

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Shpetner et al. (1996) studied this question.

synapsesocial.com/papers/6a7624901078cf7de2b25b63https://doi.org/10.1083/jcb.132.4.595
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Blockage of chemotactic peptide-induced stimulation of neutrophils by wortmannin as a result of selective inhibition of phosphatidylinositol 3-kinase.1994 · 439 citations
  2. 2Sorting of membrane components from endosomes and subsequent recycling to the cell surface occurs by a bulk flow process.1993 · 532 citations
  3. 3Phosphatidylinositol 3-Kinase Activity Is Required at a Postendocytic Step in Platelet-derived Growth Factor Receptor Trafficking1995 · 168 citations
  4. 4Endocytosis is required for the growth of vacuolar H(+)-ATPase-defective yeast: identification of six new END genes.1994 · 255 citations
  5. 5Phosphatidylinositol 3‐kinase1994 · 644 citations