The structural requirement for specific relaxant activity of benzylisoquinolines in rat smooth muscle involves an unsaturated heterocyclic ring.
No takes yet. Share an insight, caveat, or question.
Highlights unsaturated rings for specific relaxant activity in rat models; extends preclinical SAR but leaves open clinical translation.
Anselmi et al. (1992) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: