Perioperative management of patients with schizophrenia

This article is a review of publications on clinical research and recommendations for managing patients with schizophrenia in the perioperative period in surgical interventions not associated with psychopathology. An anesthesiologist may face behavioral, cognitive and emotional problems in patients with schizophrenia at all stages of the perioperative period. When anesthetizing such patients, it is necessary to take into account the undesirable side effects of antipsychotics, as well as the risk of their interaction with anesthetics. It is also known that schizophrenia often combines with cardiovascular and endocrine diseases, which further increases the risk of anesthesia. The article gives a description of the main groups of drugs for the treatment of schizophrenia — typical and atypical antipsychotics, a tactic of withdrawal or continuation of their admission during the perioperative period. The problem of neuroleptic malignant syndrome is considered — a potentially lethal complication of therapy with these drugs.