Adding a New Dimension to PH Imaging

Andrew J. Bradley; Mardi Gomberg‐Maitland

doi:10.1002/pul2.70044

January 1, 2025Pulmonary CirculationOpen Access

Adding a New Dimension to PH Imaging

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Why the study?

Does 4D flow MRI differentiate between PAH and PH-HFpEF?

Structured PICO

Does 4D flow MRI differentiate between PAH and PH-HFpEF?

P

Population

Patients with pulmonary arterial hypertension (PAH) and pulmonary hypertension-heart failure preserved ejection fraction (PH-HFpEF)

I

Intervention

4D flow MRI (4D MRI)

O

Outcome

Differentiation between PAH and PH-HFpEF using wall shear stress (WSS) and peak velocity (Vpeak)surrogate

Limitations

Between-group differences in PASP and pulmonary vascular resistance
Inability to separate cause from effect (intrinsic differences vs reflective of remodeled PA flow)

Implication

4D flow MRI is a feasible, non-invasive method that may help differentiate between PAH and PH-HFpEF by detecting differences in pulmonary artery flow profiles.

Abstract

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Discussion

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Cite This Study

Bradley et al. (2025) studied this question.

synapsesocial.com/papers/6a76425c8ffa56f63806d8f5 https://doi.org/10.1002/pul2.70044

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Adding a New Dimension to PH Imaging

Structured PICO

Limitations

Implication

Abstract

Discussion

Cite This Study

Adding a New Dimension to PH Imaging

Structured PICO

Limitations

Implication

Abstract

Discussion

Cite This Study

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