Why the study?
Does alfentanil 10 micrograms.kg-1 reduce the haemodynamic response during teaching of fibreoptic orotracheal intubation in patients under general anaesthesia?
Does alfentanil 10 micrograms.kg-1 reduce the haemodynamic response during teaching of fibreoptic orotracheal intubation in patients under general anaesthesia?
Alfentanil 10 micrograms.kg-1 effectively minimizes the haemodynamic response during fibreoptic orotracheal intubation teaching under general anaesthesia.
Alfentanil 10 μg·kg⁻¹ blunts hemodynamic responses during fiberoptic intubation teaching; supports routine use in anesthesia protocols and extends RCT evidence for this indication.
A technique for teaching fibreoptic orotracheal intubation in patients under general anaesthesia is described and evaluated. A standard general anaesthetic was administered to 60 patients presenting for elective gynaecological surgery. Patients were randomly assigned to receive either alfentanil 10 micrograms.kg-1 or a placebo, and to be intubated either by a consultant experienced in the use of the fibreoptic bronchoscope or by an inexperienced trainee under instruction. Heart rate, arterial pressure and oxygen saturation were monitored continuously. The time to achieve tracheal intubation in the trainee group was significantly prolonged (p < 0.001), but no patient developed arterial desaturation. The hypertensive response to fibreoptic intubation was suppressed in those patients who received alfentanil (p < 0.001). The increase in heart rate was not suppressed, but was attenuated when these patients were compared with those who had received the placebo (p < 0.001). Alfentanil 10 micrograms.kg-1 minimises the haemodynamic response when teaching fibreoptic orotracheal intubation under general anaesthesia.
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Hartley et al. (1994) studied this question.
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