Why the study?
Although local impedance drops predict lesion formation and some conduction gaps during PVI relate to nonendocardial connections, the incidence, characteristics, and predictors of endocardial and nonendocardial gaps during LI-guided PVI remained to be investigated.
Population
157 consecutive patients undergoing initial LI-guided extensive PVI for AF
Comparison
Endocardial vs nonendocardial conduction gaps
Design
Prospective cohort study
Authors
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Nonendocardial gaps predominate after LI-guided PVI; supports targeted carina mapping but leaves optimal strategies open.
During LI-guided PVI, approximately two-thirds of conduction gaps are nonendocardial, particularly at the carina regions, and are predicted by paroxysmal AF, lower LA volume index, and larger inferior PV diameters.
Nakamura et al. (2021) studied this question.
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