Ventricular septal rupture complicating myocardial infarction is associated with multiple coronary occlusions lacking collateral flow, and its location can be accurately predicted by regional left ventricular wall akinesis.
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Echocardiographic akinesis may localize post-MI septal rupture; observational data leave open whether absent collaterals are causal.
Miller et al. (1978) studied this question.
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