Can the current monkeypox affect the heart? A Comprehensive Systematic Review

Background Till now all symptoms of monkeypox virus aren’t known, and we still discover new symptoms associated with monkeypox. Accordingly, we aimed to summarize evidence about cardiac complications associated with monkeypox virus. Methods On Oct. 27, 2022, a systematic search of the literature was done to locate papers that discuss any cardiac complications associated with monkeypox, then data were analyzed qualtitively. Results five articles including seven cases that reported cardiovascular complications of the disease were included in the review, it was reported that five were men of which four are bisexual or gays which reveal the importance of the sexual route in the disease transmission. All of seven cases have different forms of cardiac complications such as acute myocarditis, pericarditis, pericardial effusion and myopericarditis. Most of them have evidence of systemic inflammatory response in the form of fever, myalgia, and headache. Conclusions The first study summarizes cardiac complications of monkeypox infection. It indicates the possibility of cardiac complications of monkeypox infection which can be managed by supportive treatment and complete rest for a period that may reach 6 months depending on the status of the patient.