Why the study?
Does prehospital statin and aspirin use reduce the prevalence of severe sepsis and acute lung injury/acute respiratory distress syndrome in critically ill patients?
Population
575 critically ill patients admitted to the medical or surgical intensive care unit of an academic…
Comparison
Prehospital statin therapy vs No prehospital statin therapy
Design
Cross-sectional
Follow-up
In-hospital
Authors
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Prehospital statin use was associated with lower sepsis and ALI/ARDS odds; hypothesis-generating observation leaves open a preventive role pending prospective trials.
Does prehospital statin and aspirin use reduce the prevalence of severe sepsis and acute lung injury/acute respiratory distress syndrome in critically ill patients?
Prehospital statin use is associated with a reduced risk of developing severe sepsis and acute lung injury/ARDS in critically ill patients, an effect that may be potentiated by concurrent aspirin use.
O’Neal et al. (2011) studied this question.
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