Why the study?
The association of post-implant tricuspid regurgitation and heart failure hospitalization in patients without heart failure or preexisting abnormal tricuspid regurgitation and pressure gradient remained unclear.
Does progressive tricuspid regurgitation after permanent pacemaker implantation increase the risk of heart failure hospitalization in patients without prior heart failure?
Population
1,075 transvenous PPM patients without prior valvular surgery, HF, or baseline abnormal TR/TRPG
Comparison
Progressive post-implant TR and/or elevated TRPG vs no progressive post-implant TR
Design
Single-center cohort study
Authors
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Progressive post-PPM TR may signal higher HF hospitalization risk; leaves open need for prospective monitoring trials in patients without baseline HF.
Does progressive tricuspid regurgitation after permanent pacemaker implantation increase the risk of heart failure hospitalization in patients without prior heart failure?
Progressive tricuspid regurgitation occurs in nearly 20% of patients following transvenous pacemaker implantation and is associated with a significantly increased risk of subsequent heart failure hospitalization.
Lee et al. (2020) studied this question.
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