What question did this study set out to answer?

To describe the clinical presentation, echocardiographic features, and rapid recurrence of a rare primary left atrial undifferentiated sarcoma that clinically and macroscopically mimicked a benign myxoma.

July 1, 2008Chinese Medical JournalOpen Access

A mobile mass - a left atrial undifferentiated sarcoma mimicking myxoma: a case report

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To describe the clinical presentation, echocardiographic features, and rapid recurrence of a rare primary left atrial undifferentiated sarcoma that clinically and macroscopically mimicked a benign myxoma.
Clinical, diagnostic, and surgical evaluation of a 14-year-old female presenting with fever, tachycardia, apical diastolic murmur, and an obstructive mobile left atrial mass.
Diagnostic workup included transthoracic echocardiography (TTE), surgical resection under cardiopulmonary bypass with cold cardioplegia, and histopathological analysis with immunohistochemistry (vimentin staining).
Echocardiography identified a mobile, lobulated 57 mm × 44 mm × 34 mm left atrial mass originating near the fossa ovalis and obstructing the mitral valve orifice during diastole, initially diagnosed as a benign myxoma.
Histopathology and immunohistochemistry following surgical excision revealed an undifferentiated primary cardiac sarcoma despite its gelatinous, myxoid appearance.
TTE documented tumor recurrence at 1 month postoperatively, and the patient experienced sudden cardiac death at 2 months post-resection.

Structured PICO

Population

A 14-year-old girl presenting with fever, cough, and a mobile left atrial mass mimicking a myxoma.

Intervention

Surgical excision of the tumor on cardiopulmonary bypass.

Outcome

Tumor recurrence and patient survival.hard clinical

Primary cardiac undifferentiated sarcoma can mimic benign myxoma on echocardiography and carries a poor prognosis with rapid recurrence despite surgical resection.

Limitations

CT or MRI scan was unavailable to the patient
Intraoperative frozen section was not performed

Discussion

No takes yet. Share an insight, caveat, or question.

Implication

Warrants vigilance for sarcoma in myxoma-mimicking masses; leaves open effective strategies beyond resection in this rare entity.

Cite This Study

Shao et al. (2008) studied this question.

synapsesocial.com/papers/6a765346f8a4cd622d0882ad https://doi.org/10.1097/00029330-200807020-00018

Topics

Echocardiography

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A mobile mass - a left atrial undifferentiated sarcoma mimicking myxoma: a case report

Key Points

Structured PICO

Limitations

Discussion

Implication

Cite This Study

Topics

A mobile mass - a left atrial undifferentiated sarcoma mimicking myxoma: a case report

Key Points

Structured PICO

Limitations

Discussion

Implication

Cite This Study

Also Consider

Topics

Also Consider