Microbial asymmetric reduction of ketones is a method widely used for the preparation of chiral alcohols. The present progress report deals with the basic concepts that govern enantioselectivity of enzymes and intact cells. Strategies to control the stereochemical course of microbial reductions of carbonyl compounds and the relationship of substrate structure to enantioselectivity are considered.
No takes yet. Share an insight, caveat, or question.
Sih et al. (1984) studied this question.
Synapse has enriched 3 closely related papers on similar clinical questions. Consider them for comparative context: