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Among the various anions, only cyanide induced the revival of fluoresecence of -Cu(2+) resulting in "Off-On" type sensing of cyanide, which can be monitored at pH 7.4 in 100% aqueous system, and has been applied to a microfluidic platform, in which fluorescent sensor -Cu(2+) displayed green fluorescence upon the addition of cyanide, the in vivo imaging of cyanide using Caenorhabditis elegans.
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Chung et al. (2009) studied this question.
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