Why the study?
Does sex and age affect the frequency of non-modulation in hypertensive patients?
Population
225 hypertensive inpatients (70 women, 155 men)
Comparison
Infused angiotensin II during low sodium balance vs Comparison between sexes and across age groups…
Design
Cross-sectional
Authors
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Suggests possible hormonal protection in young hypertensive women; hypothesis-generating and should not yet change practice.
Does sex and age affect the frequency of non-modulation in hypertensive patients?
Female sex hormones may confer protection against the non-modulation phenotype in young hypertensive women, which diminishes with advancing age.
Fisher et al. (1997) studied this question.
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