Answers are grounded in this paper and cite their sources.
Site creation: Enantioselective artificial metalloenzymes have been created by grafting a new active site onto bovine pancreatic polypeptide through the introduction of an amino acid capable of coordinating a copper(II) ion. This hybrid catalyst gave good enantioselectivities in the Diels-Alder and Michael addition reactions in water (see scheme) and displayed a very high substrate selectivity.
No takes yet. Share an insight, caveat, or question.
Coquière et al. (2009) studied this question.
Synapse has enriched 10 related papers. Consider them for comparative context: