Population
Purified titin protein (approximately 3 MDa polypeptide)
Design
Preclinical
Authors
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Titin interactions support its scaffolding role in sarcomeres; extends in vitro mapping but leaves open in vivo and clinical relevance.
Demonstrates that the giant myofibrillar protein titin interacts with myosin, C-protein, X-protein, and AMP-deaminase in vitro.
Soteriou et al. (1993) studied this question.
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