Fragility syndrome in patients with chronic heart failure

Heart failure has a prevalence of 26 million in the population, making it a global health priority. Current publications show that fragility syndrome reaches 79% in heart failure and is an independent predictor of mortality from cardiovascular disease. The study assessed the fragility by the Edmonton self-reported score and the Charlson comorbidity index in 36 hospitalized patients with chronic heart failure with a mean age of 66.58±1.65(44-86) years, including 20(55.6%) women and 16(44.4%) men. Fragility syndrome of varying severity was found in 16(45.5%) vs 20(55.5%) non-fragile patients with chronic heart failure with mean age 62.25±2.53 vs 70.05±1,87 years in both groups, respectively. We obtained the predominance in the group of fragile patients of women 10(62.5%) vs 6(37.5%) men. Fragile patients more frequently mentioned a decrease in physical activity during the last months 14(87.5%)vs 12(60.0%) non-fragile cases. The quality of sleep was different in the groups, so that fragile patients had more frequently a duration of sleep ≤5 hours - 9(56.3%) cases, while in the non-fragile group predominated those with 7-8 hours of sleep 8(40.0 %) patients. The mean value of the Charlson Comorbidity Index was 5.3±0.5 points.