Population
Single human heart myofibrils and demembranated, fully Ca2+-activated, human cardiac fibers
Comparison
Slack-test protocol, selective digestion of… vs Unloaded shortening velocity in demembranated…
Design
Preclinical
Authors
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Suggests titin-driven recoil may accelerate early systolic contraction in human myocardium.
Damped myofibrillar elastic recoil driven by titin could help accelerate the active contraction speed of human myocardium during early systolic shortening.
Opitz et al. (2003) studied this question.
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