Why the study?
Does androgen deprivation therapy increase the risk of incident diabetes and cardiovascular disease in men with prostate cancer?
Population
n=37,443 men of all ages diagnosed with local or regional prostate cancer in the Veterans Healthcare…
Comparison
Androgen deprivation therapy vs No androgen deprivation therapy
Design
Cohort
Follow-up
through December 31, 2005
Authors
Loading...
May warrant cardiometabolic monitoring with GnRH agonists; leaves open causality pending randomized trials.
Does androgen deprivation therapy increase the risk of incident diabetes and cardiovascular disease in men with prostate cancer?
Androgen deprivation therapy with GnRH agonists in men with prostate cancer is associated with a significantly increased risk of incident diabetes and cardiovascular events.
Keating et al. (2009) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: