What question did this study set out to answer?

To describe the diagnosis of obstructive apical hypertrophic cardiomyopathy using contrast-enhanced echocardiography following suboptimal unenhanced imaging.

August 1, 2002Echocardiography

Echocardiographic Diagnosis of Apical Hypertrophic Cardiomyopathy with Optison Contrast

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Why the study?

Does Optison contrast improve echocardiographic visualization and diagnosis of apical hypertrophic cardiomyopathy compared to native harmonic imaging in a patient with suboptimal images?

Key Points

To describe the diagnosis of obstructive apical hypertrophic cardiomyopathy using contrast-enhanced echocardiography following suboptimal unenhanced imaging.
Assessed a 61-year-old female presenting with chest pain syndrome using electrocardiography, stress nuclear myocardial perfusion scanning, and transthoracic echocardiography.
Administered 0.5 cc of intravenous Optison contrast during repeat transthoracic echocardiography to overcome suboptimal visualization from native harmonic imaging.
Electrocardiogram showed deep negative T waves and the stress nuclear scan revealed marked radioisotope uptake at the left ventricular apex.
Optison contrast echocardiography successfully resolved left ventricular apical segments, confirming obstructive apical hypertrophic cardiomyopathy and prompting referral for genetic testing.

Structured PICO

Does Optison contrast improve echocardiographic visualization and diagnosis of apical hypertrophic cardiomyopathy compared to native harmonic imaging in a patient with suboptimal images?

Population

A 61-year-old Caucasian female with a history of chest pain syndrome, abnormal stress nuclear perfusion scan showing marked increased uptake at the LV apex, and deep negative T waves on ECG.

Intervention

0.5 cc of Optison contrast given intravenously during transthoracic echocardiography

Comparator

Transthoracic echocardiography with native harmonic imaging

Outcome

Confirmation of the diagnosis of obstructive apical hypertrophic cardiomyopathysurrogate

The use of intravenous echocardiographic contrast can facilitate the diagnosis of apical hypertrophic cardiomyopathy when standard imaging is suboptimal.

Discussion

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Implication

Contrast may aid obstructive apical HCM diagnosis after suboptimal native imaging; hypothesis-generating, requiring prospective validation before wider adoption.

Cite This Study

Patel et al. (2002) studied this question.

synapsesocial.com/papers/6a76804da0847c3df1ec0dc7 https://doi.org/10.1046/j.1540-8175.2002.00521.x

Topics

Echocardiography Hypertrophic cardiomyopathy

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Implication

Contrast may aid obstructive apical HCM diagnosis after suboptimal native imaging; hypothesis-generating, requiring prospective validation before wider adoption.

Echocardiographic Diagnosis of Apical Hypertrophic Cardiomyopathy with Optison Contrast

Key Points

Structured PICO

Discussion

Implication

Cite This Study

Topics

Echocardiographic Diagnosis of Apical Hypertrophic Cardiomyopathy with Optison Contrast

Key Points

Structured PICO

Discussion

Implication

Cite This Study

Also Consider

Topics

Also Consider