A review of the pathophysiology and recent developments in perioperative renal protection for vascular and cardiac surgical patients.
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Informs perioperative renal protection strategies in cardiac and vascular surgery; leaves open optimal interventions pending prospective validation.
Acute renal failure continues to complicate the postoperative courses of our vascular and cardiac surgical patients, dramatically increasing mortality and decreasing quality of life when it occcurs. In spite of better understanding of the disease, few gains have been made in its prevention. We review its pathophysiology and discuss the most recent developments that may eventually lead to perioperative renal protection.
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Sadovnikoff et al. (1999) studied this question.
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