Population
Sarcoplasmic reticulum Ca2+-ATPase labeled with N-acetyl-N'-(5-sulfo-1-naphthyl)ethylenediamine at Cys-674
Comparison
Addition of Mg.ATP, Mn.ATP, or Ca.ATP vs Baseline or absence of ATP/different cations
Design
Preclinical
Authors
Loading...
Supports fluorescence as a reporter for SERCA phosphoenzyme formation; leaves open utility in physiological or disease models.
This basic science study demonstrates that the second phase of the Ca.ATP-induced fluorescence drop in labeled sarcoplasmic reticulum Ca2+-ATPase coincides with phosphoenzyme formation.
Suzuki et al. (1994) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: