Why the study?
Calcium channel blocker poisoning is one of the most lethal cardiac drug overdoses.
Does invasive hemodynamic monitoring guide successful treatment in severe calcium channel blocker poisoning?
Does invasive hemodynamic monitoring guide successful treatment in severe calcium channel blocker poisoning?
Invasive hemodynamic monitoring can be a crucial adjunct to guide the treatment of refractory hypotension in severe calcium channel blocker poisoning.
BACKGROUND: Calcium channel blocker poisoning is one of the most lethal cardiac drugs overdoses. Calcium and high-dose insulin infusion are the first-line therapy for symptomatic patients, and Intralipid emulsion infusion is useful for refractory cases. CASE PRESENTATION: In this report, we describe a 17-year-old Iranian girl who took 250 mg of the drug for a suicidal attempt and presented with refractory hypotension and non-cardiogenic pulmonary edema treated successfully with the guidance of invasive hemodynamic parameters. CONCLUSION: For complicated cases, in addition to supportive care and adjuvant therapy such as high-dose insulin and Intralipid, it is mandatory to utilize advanced hemodynamic monitoring to treat hypotension in severe calcium channel blocker poisoning to guide the treatment.
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Saeed et al. (2024) studied this question.
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