This case highlights the critical importance of a thorough, multi-disciplinary evaluation for potentially life-threatening vascular complications when patients with Marfan syndrome present with chest pain.
Aortic complications warrant consideration in Marfan patients with acute chest pain; this single case leaves open the need for prospective validation.
Marfan syndrome is a rare autosomal dominant disorder of the connective tissue. It results in a mutation in the Fibrillin-1 protein gene. We present a case of Marfan's syndrome in a young adult with life-threatening, sudden onset of chest pain secondary to a non-ST elevation myocardial infarction (NSTEMI) in the setting of an aortic pseudoaneurysm. Taking into consideration potential life-threatening underlying processes, a thorough and detailed methodology must be undertaken when encountering chest pain in a Marfan's syndrome patient. This case highlights the importance of utilizing a multi-disciplinary approach to the complexities of Marfan syndrome.
No takes yet. Share an insight, caveat, or question.
Cheema et al. (2022) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: