What question did this study set out to answer?

Determine whether radiofrequency catheter ablation of the slow pathway slows the ventricular response during atrial fibrillation in patients with AV nodal reentrant tachycardia.

September 1, 1995Journal of Cardiovascular Electrophysiology

Slowing of the Ventricular Rate During Atrial Fibrillation by Ablation of the Slow Pathway of AV Nodal Reentrant Tachycardia

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Why the study?

Does ablation of the slow pathway slow the ventricular response during atrial fibrillation in patients with AV nodal reentrant tachycardia?

Population

34 patients with dual AV physiology and inducible AV nodal reentrant tachycardia

Comparison

Radiofrequency catheter ablation of the slow… vs Baseline (pre-ablation)

Design

Cohort

Follow-up

1 week

Authors

JTJürgen TebbenjohannsUniversity of Hildesheim DPD. PfeifferUniversity Hospital Leipzig BSBurghard SchumacherWestpfalz Klinikum

Discussion

Member takes

Implication

May slow AF ventricular response in AVNRT; supports posterior inputs hypothesis but leaves open randomized confirmation.

Key Points

Determine whether radiofrequency catheter ablation of the slow pathway slows the ventricular response during atrial fibrillation in patients with AV nodal reentrant tachycardia.
Enrolled 34 patients with dual AV nodal physiology and inducible AV nodal reentrant tachycardia.
Induced atrial fibrillation at baseline, immediately following successful radiofrequency slow pathway ablation, and at 1-week follow-up to evaluate electrophysiological parameters.
Mean RR intervals significantly prolonged from 405 ± 91 ms at baseline to 535 ± 98 ms post-ablation and remained stable at 1 week (P < 0.01).
Minimal and maximal RR intervals during atrial fibrillation increased from 353 ± 76 ms and 500 ± 121 ms to 429 ± 84 ms and 673 ± 161 ms, respectively (both P < 0.01).
AV block cycle length increased from 343 ± 68 ms to 375 ± 60 ms acutely (P < 0.05) and 400 ± 56 ms at 1 week (P < 0.01), with effective refractory period lengthening from 282 ± 83 ms to 318 ± 81 ms (P < 0.05).

Structured PICO

Does ablation of the slow pathway slow the ventricular response during atrial fibrillation in patients with AV nodal reentrant tachycardia?

Population

34 patients with dual AV physiology and inducible AV nodal reentrant tachycardia

Intervention

Radiofrequency catheter ablation of the slow pathway

Comparator

Baseline (pre-ablation)

Outcome

Minimal, maximal, and mean RR intervals during induced atrial fibrillation immediately after ablation and at 1-week follow-upsurrogate

Ablation of the slow pathway in patients with AV nodal reentrant tachycardia significantly slows the ventricular response during induced atrial fibrillation, supporting the role of posterior inputs in AV nodal modification.

Cite This Study

Tebbenjohanns et al. (1995) studied this question.

synapsesocial.com/papers/6a768cfa8165d49cffcfef86 https://doi.org/10.1111/j.1540-8167.1995.tb00447.x

Topics

Atrial fibrillation Persistent AF management AF ablation outcomes Anticoagulation in AF

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Slowing of the Ventricular Rate During Atrial Fibrillation by Ablation of the Slow Pathway of AV Nodal Reentrant Tachycardia

Discussion

Member takes

Implication

Key Points

Structured PICO

Cite This Study

Topics

Slowing of the Ventricular Rate During Atrial Fibrillation by Ablation of the Slow Pathway of AV Nodal Reentrant Tachycardia

Discussion

Member takes

Implication

Key Points

Structured PICO

Cite This Study

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Topics

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