Asthma is associated with carotid arterial injury in children: The Childhood Origins of Asthma (COAST) Cohort
Why the study?
Is asthma and/or atopic disease associated with increased carotid intima-media thickness in adolescents?
Population
89 adolescents from the Childhood Origins of Asthma longitudinal birth cohort, mean age 15.3 years, 42%…
Comparison
Presence of asthma and/or atopic disease vs Controls free of asthma or atopic disease (n=12)
Design
Cohort
Authors
Discussion
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Member takes
Implication
May indicate early carotid injury in asthmatic children; leaves open causality and need for prospective confirmation before practice change.
Structured PICO
Is asthma and/or atopic disease associated with increased carotid intima-media thickness in adolescents?
P
Population
89 adolescents from the Childhood Origins of Asthma (COAST) longitudinal birth cohort, mean age 15.3 years, 42% female, including children with asthma and/or atopic disease and healthy controls.
I
Intervention
Presence of asthma and/or atopic disease
C
Comparator
Controls free of asthma or atopic disease (n=12)
O
Outcome
Far wall right carotid bifurcation (RCB) and common carotid artery (RCCA) intima-media thickness (IMT)surrogate
Adolescents with asthma and atopic disease show evidence of early subclinical arterial injury, suggesting a potential need for early cardiovascular risk monitoring in this population.
Cite This Study
Tattersall et al. (2018) studied this question.