Drug-coated balloons for de novo coronary lesions: results from the Valentines II trial

103 patients (109 lesions) with stable or unstable angina, and/or documented ischaemia on stress testing with de novo coronary lesions of >50% stenosis. Mean age 62.6, 79.6% men. Multinational registry.

Plain old balloon angioplasty (POBA) followed by second-generation DIOR drug-coated balloon (DCB) treatment, with bail-out bare metal stenting (BMS) left at the operator's discretion for suboptimal angiographic success.

Major adverse cardiac events (MACE; composite of all-cause death, myocardial infarction [MI], target vessel revascularisation [TVR] and vessel thrombosis) at six to nine months.composite