Why the study?
The authors sought to improve minimally-invasive estimation of coronary stenosis severity.
A novel method combining geometry and attenuation gradients to assess flow distribution ratios may improve minimally-invasive estimation of coronary stenosis severity.
Proposed hybrid stenosis estimation may improve noninvasive assessment; leaves open prospective validation before clinical use.
We suggest improving minimally-invasive stenosis severity estimation, using a combination of existing geometry-based methods with Transluminal Attenuation Gradient measurements. Instead of local flow values, the method uses flow distribution ratios along the entire tree. The tree geometry is used to derive a lumped model and predict the 'theoretical' ratios in each bifurcation, while attenuation measurements are used for extracting 'actual' ratios. The discrepancies between the measured and the theoretical values are utilized to assess a functional degree of stenosis. Our experimental and numerical analyses show that the quantitative value of discrepancy is proportional to stenosis severity, regardless of boundary conditions.
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Avrahami et al. (2021) studied this question.
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