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March 25, 2005AJP Heart and Circulatory Physiology

Analysis of blood flow in the entire coronary arterial tree

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Population

Computer reconstruction of the entire coronary arterial tree of the porcine heart down to the first…

Design

Preclinical

Authors

NMNishant MittalYZYi ZhouCLC. Linares

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Overview

Animal-derived coronary flow model offers reference values; leaves open translation to human physiology and pathology.

Structured PICO

P
Population
Computer reconstruction of the entire coronary arterial tree of the porcine heart down to the first capillary branch based on previously measured morphometric data
I
Intervention
Computational hemodynamic analysis of blood flow distribution based on conservation of mass and momentum
O
Outcome
Pressure and flow throughout the coronary arterial tree, diameter-flow relationship, and total arterial equivalent resistance

The study yields a predictive computational model of normal coronary blood flow that can serve as a physiological reference state for studying pathological changes.

Cite This Study

Mittal et al. (2005) studied this question.

synapsesocial.com/papers/6a769a3e5f7f0b63027d1fa2https://doi.org/10.1152/ajpheart.00730.2004
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