Key result
A computer model of a porcine coronary artery tree showed a linear relationship between coronary blood flow and the sum of arterial branch lengths, and a 3/4 power relation with lumen volume.
Population
Computer model of a porcine coronary artery tree including a network of millions of vessels down to the…
Design
Preclinical
Authors
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May enable angiography-derived FFR models; leaves open human validation before clinical use.
Arterial branch lengths or lumen volumes can predict expected maximum blood flow, providing a theoretical basis for calculating fractional flow reserve entirely from angiographic data.
Molloi et al. (2007) studied Coronary artery disease. Sum of arterial branch lengths or lumen volume was evaluated on Relationship between coronary blood flow and arterial branch lengths or lumen volume. A computer model of a porcine coronary artery tree showed a linear relationship between coronary blood flow and the sum of arterial branch lengths, and a 3/4 power relation with lumen volume.
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