Antithrombotic and Thrombolytic Therapies for Acute Myocardial Infarction
Why the study?
Do antithrombotic and thrombolytic therapies reduce mortality and ischemic events in patients with acute myocardial infarction?
Population
Patients with suspected acute myocardial infarction
Design
Review
Authors
Discussion
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Member takes
Implication
Reinforces aspirin and early thrombolysis benefits in AMI; leaves open optimal use with modern PCI strategies.
Structured PICO
Do antithrombotic and thrombolytic therapies reduce mortality and ischemic events in patients with acute myocardial infarction?
P
Population
Patients with suspected acute myocardial infarction
I
Intervention
Antithrombotic therapy (aspirin, heparin, direct thrombin inhibitors) and thrombolytic therapy
O
Outcome
Vascular mortality, reinfarction, and strokehard clinical
Aspirin and early thrombolytic therapy provide substantial mortality and morbidity benefits in acute myocardial infarction and should be widely utilized.
Cite This Study
Godfried et al. (1996) studied this question.