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In the July issue of Diabetes Care , we read with interest the study by Zangh et al. (1). They revisited material from the Diabetes Control and Complications Trial database in order to search for potential prognostic factors of developing retinopathy in patients with extreme (either good or poor) metabolic control, but who were free of the complication at baseline. The development and progression of retinopathy was defined by a three-step change or more, according to the Early Treatment Retinopathy Study protocol, on stereoscopic color fundus photographs. Their conclusion was that other than duration of diabetes and metabolic control, BMI had a significant predictive value. We found a similar influence of BMI in our population of …
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Dorchy et al. (2002) studied this question.
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