Hypercalcemia is the most common para-endocrine disorder associated with ovarian neoplasms, 14 such cases having been reported in the world's literature including 3 serous cystadenocarcinomas, 2 mesonephromas, 1 dysgerminoma, 1 undifferentiated carcinoma, and 1 “hypernephroid carcinoma.” The present paper is a report of an additional case of mesonephroma associated with clinical and chemical evidence of hypercalcemia which remitted following surgical excision of the lesion. Mesonephromas of the ovary have a disproportionate high incidence of hypercalcemia in comparison with other ovarian neoplasms. The etiology of this association is obscure.
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Ferenczy et al. (1971) studied this question.
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