Myocardial and renal protective effects of Dexmedetomidine vs Magnesium sulphate in patients undergoing elective open abdominal aortic surgery

Background: After abdominal aortic aneurysm surgery, the likelihood of postoperative myocardial infarction is seven percent, but likelihood of postoperative cardiac problems without signs of ischemic damage is thirty-six percent. Aim: goal of research had been to assess perioperative myocardial protective impact of dexmedetomidine and magnesium sulphate in high‑risk studied cases undergoing aortic vascular surgery. Methods: This randomized double blinded research had been being done in cardiothoracic & vascular surgery center, Mansoura university from May 2023 to October 2023 after approval from institutional review board of faculty of Medicine Mansoura University with obtaining a written informed consent from all studied cases. Results: there had been no variation among studied groups as regard cTnI and CKMB, and there had been no variation among studied groups as regard CC & UOP. Conclusion: Using dexmedetomidine throughout cardiac surgery protected the heart & kidneys, as seen by reduced levels of myocardial- & kidney-specific proteins in the urine & higher creatinine clearance.