What question did this study set out to answer?

To assess how the injection rate of contrast medium affects the timing and intensity of pancreatic and hepatic enhancement during abdominal helical computed tomography.

January 1, 1999Radiology

Effect of Injection Rate of Contrast Medium on Pancreatic and Hepatic Helical CT

View Full Paper

Ask AI

Bookmark

Authors

MTMitchell TublinThomas Jefferson University FTFranklin N. TesslerUniversity of Alabama at Birmingham SCSam L. ChengPSA (United States)

Discussion

Member takes

Implication

Comparative study demonstrates higher and faster peak pancreatic and hepatic enhancement at higher contrast injection rates in adults, indicating a need for earlier scan timing.

Key Points

To assess how the injection rate of contrast medium affects the timing and intensity of pancreatic and hepatic enhancement during abdominal helical computed tomography.
Evaluated 64 adult patients undergoing contrast-enhanced abdominal helical CT with 150 mL of contrast medium delivered at either 2.5 mL/sec (n=32) or 5.0 mL/sec (n=32).
Obtained serial scans at 5-second intervals (with an 8-second intermediate breathing interval) to generate time-attenuation curves and compared enhancement parameters using Student's t-test.
Peak enhancement level and time to peak enhancement differed significantly between injection rates for both organs (P ≤ .002), with faster and greater enhancement at 5.0 mL/sec.
At 2.5 mL/sec, the pancreas peaked at 65 HU at 69 seconds and the liver peaked at 58 HU at 87 seconds.
At 5.0 mL/sec, the pancreas reached a higher peak of 84 HU at 43 seconds, and the liver reached a peak of 75 HU at 63 seconds.

Cite This Study

Tublin et al. (1999) studied this question.

synapsesocial.com/papers/6a76b737c5ab23c76cec1eff https://doi.org/10.1148/radiology.210.1.r99ja2197

View Full Paper

Ask AI

Bookmark

Implication

Comparative study demonstrates higher and faster peak pancreatic and hepatic enhancement at higher contrast injection rates in adults, indicating a need for earlier scan timing.

Effect of Injection Rate of Contrast Medium on Pancreatic and Hepatic Helical CT

Discussion

Member takes

Implication

Key Points

Cite This Study

Effect of Injection Rate of Contrast Medium on Pancreatic and Hepatic Helical CT

Discussion

Member takes

Implication

Key Points

Cite This Study

Also Consider

Also Consider