Key result
Morning circadian variation is linked to higher forearm vascular resistance and increased acute cardiovascular events.
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A morning increase in the risk of acute cardiovascular disorders — transient myocardial ischemia, myocardial infarction, sudden cardiac death, and stroke —is now well documented and widely accepted by both the medical profession and the public. Over the past five years, several investigators have demonstrated that this apparent curiosity can offer clues to the mechanisms of onset of acute cardiovascular disease. The article by Panza et al. in this issue of the Journal 1 is an important addition to this emerging field of study.The authors demonstrated convincingly in normal subjects that forearm vascular resistance, as determined by plethysmography, is higher . . .
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Muller et al. (1991) conducted an editorial in Acute cardiovascular disorders. Circadian variation (morning hours) was evaluated on Forearm vascular resistance and acute cardiovascular disorders. Circadian variation is associated with a morning increase in acute cardiovascular disorders and higher forearm vascular resistance in normal subjects.
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