Why the study?
Does high-field strength MRI detect abnormal signal intensities in the thalamus and putamen of patients with multiple sclerosis?
Does high-field strength MRI detect abnormal signal intensities in the thalamus and putamen of patients with multiple sclerosis?
High-field MRI identifies decreased T2 signal in the thalamus and putamen of MS patients, likely related to iron accumulation.
High-field strength (1.5 Tesla) magnetic resonance imaging in 15 patients with multiple and extensive white-matter lesions and clinically definite multiple sclerosis delineated a previously undescribed finding of abnormally decreased signal intensity on T2-weighted images in the thalamus and putamen. The decreased signal intensity (preferential decreased T2 relaxation time) is most likely to be related to abnormally increased iron accumulation causing local magnetic field heterogeneities.
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Drayer et al. (1987) studied this question.
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