Why the study?
Single ventricle physiology remains inadequately understood, motivating a review of preclinical computational and experimental modeling proposed to advance clinical management after Fontan-type surgical corrections.
Design
Review
Authors
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Preclinical models may guide individualized Fontan planning; leaves open prospective validation before clinical adoption.
Preclinical computational and experimental models offer promising avenues for patient-specific simulations and surgical planning in complex congenital heart diseases like Fontan circulation.
Escher et al. (2025) studied this question.
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