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Case report reveals cutaneous metastasis in laryngeal carcinoma, suggesting importance of monitoring skin lesions.
Cutaneous metastasis from laryngeal squamous cell carcinoma (LSCC) is rare and is generally associated with advanced disease and poor prognosis. It often reflects aggressive tumor behavior and may occur in conjunction with systemic metastasis. We report the case of an 83-year-old Han Chinese man diagnosed with supraglottic LSCC. Owing to his advanced age, the patient underwent surgical resection alone without adjuvant radiotherapy or chemotherapy. Four months after surgery, a solitary cutaneous metastatic lesion developed on the ipsilateral neck. The lesion was completely excised, and no local recurrence or additional distant metastases have been detected during follow-up to date. This case highlights the importance of maintaining a high index of suspicion for cutaneous metastasis when new skin lesions arise during follow-up of patients with laryngeal carcinoma. Early recognition and prompt management may facilitate timely intervention. In addition, this report adds to the existing literature by illustrating an uncommon metastatic presentation of LSCC and its clinical course.
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Zhang et al. (2026) studied this question.
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