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Anti-Neuronal Antibodies in Patients with Sjögren’s Syndrome and Acute Cerebellar Ataxia: Two Case Reports

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Case reports reveal anti-neuronal antibodies may aid diagnosis in Sjögren’s syndrome neurological involvement.

This report examines the presence of anti-neuronal antibodies in patients with Sjögren's syndrome and acute cerebellar ataxia.
Presented two cases of women with acute cerebellar ataxia following Sjögren's syndrome diagnosis.
Analyzed serum and cerebrospinal fluid for antibodies and neurological responses.
Compared findings against five control patients without neurological symptoms.
One patient had unique antibody reactivity on rat brain sections after indirect immunohistochemistry.
The second patient displayed anti-glutamic acid decarboxylase in both serum and cerebrospinal fluid.
Control patients did not demonstrate any anti-neuronal antibodies.

Şanlı et al. (2026) studied this question.

View Full Paper

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View Full Paper

Ask AI

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Authors

Case reports reveal anti-neuronal antibodies may aid diagnosis in Sjögren’s syndrome neurological involvement.

This report examines the presence of anti-neuronal antibodies in patients with Sjögren's syndrome and acute cerebellar ataxia.
Presented two cases of women with acute cerebellar ataxia following Sjögren's syndrome diagnosis.
Analyzed serum and cerebrospinal fluid for antibodies and neurological responses.
Compared findings against five control patients without neurological symptoms.
One patient had unique antibody reactivity on rat brain sections after indirect immunohistochemistry.
The second patient displayed anti-glutamic acid decarboxylase in both serum and cerebrospinal fluid.
Control patients did not demonstrate any anti-neuronal antibodies.

Şanlı et al. (2026) studied this question.

View Full Paper

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