What question did this study set out to answer?

This study aimed to evaluate the impact of multiplex PCR-based identification on clinical outcomes in hospitalized pediatric patients with positive blood cultures.

August 8, 2026Microbiology SpectrumOpen Access

Implementation of multiplex PCR-based blood culture identification among hospitalized pediatric patients at a tertiary care center

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This study aimed to evaluate the impact of multiplex PCR-based identification on clinical outcomes in hospitalized pediatric patients with positive blood cultures.
Conducted a case-control cohort study with 150 retrospective and 150 prospective patients.
Compared outcomes of conventional blood culture with the BCID2 panel.
Antimicrobial recommendations were provided based on BCID2 results.
Median time to targeted therapy was significantly shorter at 17.0 hours with BCID2 versus 24.2 hours for conventional culture (P=0.014).
BCID2 implementation prompted antimicrobial modification in 28.8% of cases (38/132).
BCID2 was a significant predictor of rapid antimicrobial optimization (aOR 2.68; 95% CI 1.17–6.14; P=0.019).

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Implication

Randomized trial shows improved clinical outcomes in pediatric patients through rapid pathogen identification, suggesting better therapy management.

Cite This Study

Sripol et al. (2026) studied this question.

synapsesocial.com/papers/6a76db2df12abadc79816484 https://doi.org/10.1128/spectrum.01571-26

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Implication

Randomized trial shows improved clinical outcomes in pediatric patients through rapid pathogen identification, suggesting better therapy management.

Implementation of multiplex PCR-based blood culture identification among hospitalized pediatric patients at a tertiary care center

Key Points

Discussion

Implication

Cite This Study

Implementation of multiplex PCR-based blood culture identification among hospitalized pediatric patients at a tertiary care center

Key Points

Discussion

Implication

Cite This Study

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