Myo1e exhibits rapid ADP release and weak actin affinity, suggesting that subclass-1 myosin-Is are tuned for rapid sliding in regions of high cross-linked actin filament concentrations.
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Myo1e kinetics suggest subclass-1 tuning for rapid sliding; leaves open relevance to human cardiac contractility.
Mezgueldi et al. (2002) studied this question.
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