Why the study?
Current methods for isolating adult mouse cardiomyocytes pose technical barriers, require extensive training or continuous manual operation, and rely on stereoscopic microscopy.
This study presents a simplified, microscope-free method for isolating adult mouse cardiomyocytes and performing epicardial activation mapping, potentially lowering technical barriers for basic cardiovascular research.
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May simplify adult mouse cardiomyocyte isolation; leaves open validation of yield, viability, and functional utility.
Zhang et al. (2021) studied this question.
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